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239000011780 sodium chloride Substances 0.000 claims abstract description 97.

150000001875 compounds Chemical class 0.000 claims abstract description 227.

230000002401 inhibitory effect Effects 0.000 title description 39.

-1 3,4-disubstituted-1h-pyrrolopyridines Chemical class 0.000 title claims abstract description 75.

Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) Filing date Publication date Priority claimed from US201361916953P external-priority Application filed by Pfizer Inc filed Critical Pfizer Inc Publication of CA2933767A1 publication Critical patent/CA2933767A1/en Application granted granted Critical Publication of CA2933767C publication Critical patent/CA2933767C/en Status Active legal-status Critical Current Anticipated expiration legal-status Critical Links Original Assignee Pfizer Inc Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Kurumbail Patrick Robert Verhoest Antonia Friederike STEPAN Current Assignee (The listed assignees may be inaccurate. Wager Lei Zhang Jaclyn Louise HENDERSON Ravi G.

( en Inventor Paul Galatsis Matthew Merrill Hayward Bethany Lyn KORMOS Travis T. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) Active Application number CA2933767A Other languages French ( fr)

Google Patents Novel 3,4-disubstituted-1h-pyrrolopyridines and 4,5-disubstituted-7h-pyrrolopyridazines as lrrk2 inhibitorsĭownload PDF Info Publication number CA2933767C CA2933767C CA2933767A CA2933767A CA2933767C CA 2933767 C CA2933767 C CA 2933767C CA 2933767 A CA2933767 A CA 2933767A CA 2933767 A CA2933767 A CA 2933767A CA 2933767 C CA2933767 C CA 2933767C Authority CA Canada Prior art keywords pyrrolo morpholin pyridin pyridine methyl Prior art date Legal status (The legal status is an assumption and is not a legal conclusion. Google Patents CA2933767C - Novel 3,4-disubstituted-1h-pyrrolopyridines and 4,5-disubstituted-7h-pyrrolopyridazines as lrrk2 inhibitors CA2933767C - Novel 3,4-disubstituted-1h-pyrrolopyridines and 4,5-disubstituted-7h-pyrrolopyridazines as lrrk2 inhibitors